SIH-350
C-646
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- SIH-350
- Zusätzliche Namen:
- 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]- 4,5-dihydro-3-methyl-5-oxo-1Hpyrazol- 1-yl]benzoic acid
- Molekulargewicht:
- 445.4
- Reinheit:
- >98%
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- CAS Number:
- 328968-36-1
- ABP:
- No Import Docs
- Weitere Details:
- C-646 is a potent and selective inhibitor of the histone acetyltransferase p300/CBP, with a Ki of 400 nM. In neuroscience, C-646 has been shown to enhance synaptic plasticity and memory formation, particularly in fear extinction paradigms. It also promotes tau deacetylation, thereby reducing levels of pathogenic phosphorylated tau (p-tau), a hallmark of Alzheimer's disease. These properties position C-646 as a promising epigenetic modulator for neurodegenerative disease research, offering insights into chromatin remodeling and transcriptional regulation in neuronal health and disease.
- Versandbedingungen:
- Ambient