BIX-01294

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SKU:: SIH-347
Zusätzliche Namen:: 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride; N-(1-Benzyl-4-piperidinyl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-quinazolinamine trihydrochloride
Molekulargewicht:: 600.02
Reinheit:: >98%
Quelle:: Synthetic
Lagerbedingungen:: -20[o]C
Hersteller:: StressMarq Biosciences
CAS Number:: 935693-62-2
ABP:: No Import Docs
Weitere Details:: BIX-01294 is a selective inhibitor of G9a and G9a-like protein histone lysine methyltransferases, with IC50 values of 0.7 and 1.7 uM, respectively. It modulates H3K9me2 levels in mammalian cells and has been instrumental in studies of epigenetic regulation and cellular reprogramming. In neuroscience, BIX-01294's ability to alter chromatin states and gene expression profiles makes it a valuable tool for investigating neurodevelopmental processes and neuroplasticity. Its role in facilitating the induction of pluripotent stem cells also opens avenues for regenerative medicine and modeling of neurological diseases. Although primarily used in stem cell and cancer research, its epigenetic effects are increasingly relevant to understanding and potentially treating neurodegenerative disorders.