SIH-342
MDBN
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- SIH-342
- Zusätzliche Namen:
- 3,4-Methylenedioxy-B Beta-nitrostyrene; 5-[(E)-2-Nitrovinyl]-1,3-benzodioxole
- Molekulargewicht:
- 193.2
- Reinheit:
- >98%
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- CAS Number:
- 1485-00-3
- ABP:
- No Import Docs
- Weitere Details:
- MDBN is an irreversible inhibitor of the AAA-ATPase p97, also known as valosin-containing protein (VCP), with an IC50 below 10 uM. p97 plays a central role in protein homeostasis, including ER-associated degradation (ERAD), autophagy, and stress granule dynamics. Mutations in p97 are linked to neurodegenerative disorders such as inclusion body myopathy and frontotemporal dementia. MDBN offers a pharmacological approach to modulate p97 activity and investigate its role in neuronal proteostasis and neurodegeneration.
- Versandbedingungen:
- Ambient