SIH-336
Thalidomide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- SIH-336
- Zusätzliche Namen:
- (+/-)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione, N-(2,6-dioxo-3-piperidinyl)phthalim-ide
- Molekulargewicht:
- 258.2
- Reinheit:
- >98%
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- CAS Number:
- 50-35-1
- ABP:
- No Import Docs
- Weitere Details:
- Thalidomide binds to the E3 ubiquitin ligase complex involving CRBN, DDB1, and Cul4A, inhibiting ligase activity. It suppresses TNF synthesis and angiogenesis. In neuroscience, Thalidomide is explored for its immunomodulatory effects and potential to modulate neuroinflammation and neurovascular integrity, although caution is warranted due to its teratogenic properties.
- Versandbedingungen:
- Ambient