KOA0866
Mouse EGFR ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0866
- Zusätzliche Namen:
- EGF R, EGFR, Epidermal growth factor receptor, erbb 1, Erbb1, erbb-1, HER1, PIG61|EGFR
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Mouse
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: L25-S647
- Spezies:
- Mouse
- Uniprot:
- Q01279
- Synonyme:
- 9030024J15Rik;AI552599;avian erythroblastic leukemia viral (v-erb-b) oncogene homolog;epidermal growth factor receptor;Erb;Erbb;Err;Errb1;Errp;Wa;wa-2;wa2;Wa5;waved 2
- Weitere Details:
- The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. It is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). EGFR exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor A Alpha (TGFA Alpha). EGFR and its ligands are cell signaling molecules involved in diverse cellular functions, including cell proliferation, differentiation, motility, and survival, and in tissue development. Mutations that lead to EGFR overexpression (known as upregulation) or overactivity have been associated with a number of cancers, including lung cancer and glioblastoma multiforme. In this latter case a more or less specific mutation of EGFR, called EGFRvIII is often observed.
- Versandbedingungen:
- Blue Ice