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KOA0860

Human Caspase 3 ELISA Kit

Eine Lieferung in diese Region ist nicht möglich.

SKU:
KOA0860
Zusätzliche Namen:
CASP-3, CASP3, CASP 3, Caspase-3, Caspase3, Caspase 3, SCA-1, SCA 1, SCA1|CASP3
Anwendung:
ELISA
Lagerbedingungen:
Please refer to datasheet
Hersteller:
Rockland Inc
Reaktivitäten:
Human
Immunogen:
Expression system for standard: E.coli; Immunogen sequence: S29-D175&A183-H277
Spezies:
Human
Uniprot:
P42574
Synonyme:
apopain;CASP-3;caspase 3, apoptosis-related cysteine peptidase;caspase 3, apoptosis-related cysteine protease;caspase-3;CPP-32;CPP32;CPP32B;cysteine protease CPP32;PARP cleavage protease;procaspase3;protein Yama;SCA-1;SREBP cleavage activity 1
Weitere Details:
Caspase-3 is a caspase protein that is encoded by the CASP3 gene. This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Versandbedingungen:
Blue Ice