Mouse TIMP-4 ELISA Kit

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SKU:: KOA0802
Zusätzliche Namen:: Metalloproteinase inhibitor 4, TIMP 4, TIMP metallopeptidase inhibitor 4, Tissue inhibitor of metalloproteinase 4, Tissue inhibitor of metalloproteinases 4|TIMP4
Anwendung:: ELISA
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Reaktivitäten:: Mouse
Immunogen:: Expression system for standard: NSO; Immunogen sequence: C30-P224
Spezies:: Mouse
Uniprot:: Q9JHB3
Synonyme:: metalloproteinase inhibitor 4;TIMP;Timp-4;tissue inhibitor of metalloproteinases 4
Weitere Details:: Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene. This gene belongs to the tissue inhibitor of metalloproteinases gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. TIMP4 gene is mapped to chromosome 3p25. TIMP4 gene contains 5 exons that span 6 kb of genomic DNA. The gene is expressed as a 1.4-kb transcript abundant in heart and present at low levels in several other tissues. Expressed TIMP4 inhibits MMPs in vitro. What's more, TIMP-4 binds both progelatinase A and the C domain in a similar manner to that of TIMP-2.