KOA0766
Mouse DMP-1 ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0766
- Zusätzliche Namen:
- ARHP, ARHR, AV020965, Dentin matrix acidic phosphoprotein 1, Dentin matrix protein 1, DENTMAT, DMP 1, Dmp, MGC130441, PP, Serine rich acidic phosphoprotein|DMP1
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Mouse
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: L17-Y503
- Spezies:
- Mouse
- Uniprot:
- O55188
- Synonyme:
- AG1;AV020965;dentin matrix acidic phosphoprotein 1;Dmp;DMP-1;PP;serine rich acidic phosphoprotein
- Weitere Details:
- Dentin matrix acidic phosphorprotein 1 is a protein that in humans is encoded by the DMP1 gene. It belongs to the small integrin-binding ligand N-linked glycoprotein(SIBLING) family of secreted phosphoproteins. This gene is mapped to 4q22.1. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. In undifferentiated osteoblasts, DMP-1 is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation, the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals.
- Versandbedingungen:
- Blue Ice