Human Ficolin-3 ELISA Kit

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SKU:: KOA0743
Zusätzliche Namen:: Collagen/fibrinogen domain containing lectin 3 p35, Collagen/fibrinogen domain containing protein 3, FCN 3, FCNH, Ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen), Ficolin (collagen/fibrinogen domain containing) 3, Ficolin 3, H ficolin, HAKA1, Hakata antigen, MGC22543|FCN3
Anwendung:: ELISA
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Reaktivitäten:: Human
Immunogen:: Expression system for standard: NSO; Immunogen sequence: Q24-R299
Spezies:: Human
Uniprot:: O75636
Synonyme:: collagen/fibrinogen domain-containing lectin 3 p35;collagen/fibrinogen domain-containing protein 3;FCNH;ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen);ficolin-3;H-ficolin;HAKA1;Hakata antigen
Weitere Details:: Ficolin-3, also known as HAKA1, is a protein that in humans is encoded by the FCN3 gene. It is mapped to 1p36.11. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Ficolin-3 is expressed as a 35-kD protein that reacts with systemic lupus erythematosus sera. Ficolin-3 does not bind fibronectin(FN1), elastin(ELN), or zymosan, and the lectin activity of the Ficolin-3 is calcium independent. Homozygosity for the variant in the FCN3 gene results in a recessive complement deficiency syndrome.