KOA0727
Human Midkine ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0727
- Zusätzliche Namen:
- Amphiregulin-associated protein, ARAP, Mdk, Midgestation and kidney protein, Midkine, MK, MK_HUMAN, Neurite outgrowth-promoting factor 2, Neurite outgrowth-promoting protein|MDK
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Human
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: K23-D143
- Spezies:
- Human
- Uniprot:
- P21741
- Synonyme:
- amphiregulin-associated protein;ARAP;midgestation and kidney protein;midkine;MK;NEGF2;neurite growth-promoting factor 2;neurite outgrowth-promoting factor 2;Neurite outgrowth-promoting protein;retinoic acid inducible factor
- Weitere Details:
- Midkine(MK or MDK) also known as neurite growth-promoting factor 2(NEGF2) is a protein that in humans is encoded by the MDK gene. Midkine is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin(NEGF1, 46% homologous with MK). It is a nonglycosylated protein, composed of two domains held by disulfide bridges. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair. MK is pleiotropic, capable of exerting activities such as cell proliferation, cell migration, angiogenesis and fibrinolysis. A molecular complex containing receptor-type tyrosine phosphatase zeta(PTPZ Zeta), low density lipoprotein receptor-related protein(LRP1), anaplastic leukemia kinase(ALK) and syndecans is considered to be its receptor.
- Versandbedingungen:
- Blue Ice