KOA0697
Human LIFR ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0697
- Zusätzliche Namen:
- CD118, CD118 antigen, FLJ98106, FLJ99923, Leukemia inhibitory factor receptor alpha, Leukemia inhibitory factor receptor, LIF R, LIF receptor, LIF-R, Lifr, LIFR_HUMAN, SJS2, STWS, SWS|LIFR
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Human
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: Q45-S833
- Spezies:
- Human
- Uniprot:
- P42702
- Synonyme:
- CD118;CD118 antigen;leukemia inhibitory factor receptor;leukemia inhibitory factor receptor alpha;LIF receptor alpha;LIF-R;SJS2;STWS;SWS
- Weitere Details:
- LIFR, also known as CD118(Cluster of Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. This gene encodes a protein that belongs to the type I cytokine receptor family. It is mapped to 5p31.1. The LIF receptor(LIFR) is the low-affinity binding chain that, together with the high-affinity converter subunit gp130, forms a high-affinity receptor complex that mediates the action of the leukemia-inhibitory factor. LIF is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, together with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland.
- Versandbedingungen:
- Blue Ice