KOA0656
Mouse TNFRSF13B - TACI ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0656
- Zusätzliche Namen:
- CD267, TNFRSF13B, TR13B_HUMAN, Transmembrane activator and CAML interactor, Tumor necrosis factor receptor superfamily member 13B|TNFRSF13B
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Mouse
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: A2-C128
- Spezies:
- Mouse
- Uniprot:
- Q9ET35
- Synonyme:
- 1200009E08Rik;Ta;Taci;transmembrane activator and calcium-modulating and cyclophilin ligand interactor;transmembrane activator and CAML interactor;tumor necrosis factor receptor superfamily member 13B
- Weitere Details:
- Tumor necrosis factor receptor superfamily member 13B, also known as TNFRSF13B or more commonly as TACI, is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system. TACI controls T cell-independent B cell antibody responses, isotype switching, and B cell homeostasis. TACI is a lymphocyte-specific member of the tumor necrosis factor(TNF) receptor superfamily. It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand(CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. These proteins signal through TACI inducing activation of several transcription factors including NFAT, AP-1, and NF-kappa-B which then modulate cellular activities. Defects in the function of TACI can lead to immune system diseases.
- Versandbedingungen:
- Blue Ice