KOA0616
Human TNFRSF9 - 4-1BB ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0616
- Zusätzliche Namen:
- 4-1BB, 4-1BB ligand receptor, CD137, CD137 antigen, CDw137, Homolog of mouse 4 1BB, ILA, Induced by lymphocyte activation (ILA), Interleukin activated receptor homolog of mouse Ly63, Receptor protein 4 1BB, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, TNR9_HUMAN, Tumor necrosis factor receptor superfamily member 9|TNFRSF9
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Human
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: L24-Q186
- Spezies:
- Human
- Uniprot:
- Q07011
- Synonyme:
- 4-1BB;4-1BB ligand receptor;CD137;CD137 antigen;CDw137;homolog of mouse 4-1BB;ILA;induced by lymphocyte activation (ILA);interleukin-activated receptor, homolog of mouse Ly63;receptor protein 4-1BB;T cell antigen ILA;T-cell antigen 4-1BB homolog;T-cell antigen ILA;tumor necrosis factor receptor superfamily member 9
- Weitere Details:
- CD137 is a member of the tumor necrosis factor(TNF) receptor family. Its alternative names are tumor necrosis factor receptor superfamily member 9(TNFRSF9), 4-1BB and induced by lymphocyte activation(ILA). CD137 gene was localized to chromosome 1p36.Members of this receptor family and their structurally related ligands are important regulators of a wide variety of physiological processes and play an especially important role in the regulation of immune responses. CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. The best characterized activity of CD137 is its costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
- Versandbedingungen:
- Blue Ice