KOA0601
Human Progranulin ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0601
- Zusätzliche Namen:
- Acrogranin, CLN11, GEP, GP88, Granulin A, Granulin B, Granulin C, Granulin D, Granulin E, Granulin epithelin, Granulin F, Granulin G, Granulin-7, Granulins, GRN, GRN_HUMAN, PC cell derived growth factor, PCDGF, PEPI, PGRN, Proepithelin, Progranulin|GRN
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Human
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: T18-L593
- Spezies:
- Human
- Uniprot:
- P28799
- Synonyme:
- acrogranin;CLN11;epithelin;GEP;glycoprotein 88;glycoprotein of 88 Kda;GP88;granulin-epithelin;granulins;PC cell-derived growth factor;PCDGF;PEPI;PGRN;proepithelin;progranulin
- Weitere Details:
- Granulin, also known as Proepithelin(PEPI) is a protein that in humans is encoded by the GRN gene. This gene is mapped to 17q21.31. Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.
- Versandbedingungen:
- Blue Ice