KOA0596
Human complement C5a ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0596
- Zusätzliche Namen:
- anaphylatoxin C5a analog, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5, CO5_HUMAN, complement C5, Complement C5 alpha chain, Complement component 5, CPAMD4, ECLZB|C5
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Human
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: T678-R751
- Spezies:
- Human
- Uniprot:
- P01031
- Synonyme:
- anaphylatoxin C5a analog;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4;C5a;C5a anaphylatoxin;C5b;C5D;complement C5;complement component 5;CPAMD4;ECLZB;prepro-C5
- Weitere Details:
- C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.
- Versandbedingungen:
- Blue Ice