KOA0576
Human MIA ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0576
- Zusätzliche Namen:
- CD RAP, melanoma inhibitory activity, Melanoma inhibitory activity protein, Melanoma-derived growth regulatory protein, Mia, MIA_HUMAN|MIA
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Human
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: G25-131Q
- Spezies:
- Human
- Uniprot:
- Q16674
- Synonyme:
- CD-RAP;melanoma inhibitory activity;Melanoma inhibitory activity protein;melanoma-derived growth regulatory protein
- Weitere Details:
- Melanoma Inhibiting Activity(MIA), also known as cartilage-derived retinoic acid-sensitive protein(CD-RAP), is an approximately 11-15 kDa protein that is expressed as a noncovalent homodimer. MIA is structurally related to OTOR/Otoraplin and MIA-2 in a small family of secreted proteins with one SH3 domain(1-3). And the MIA gene was mapped to 19q13.32-q13.33 by fluorescence in situ hybridization. Beside, It is a marker for malignant melanoma. MIA functions as a chemoattractant for mesenchymal stem cells and enhances their BMP-2 and TGF-beta3 induced differentiation into chondrocytes . MIA-deficient mice exhibit delayed chondrocyte differentiation but enhanced chondrocyte proliferation and cartilage repair .
- Versandbedingungen:
- Blue Ice