KOA0553
Human Furin ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0553
- Zusätzliche Namen:
- Dibasic processing enzyme, Dibasic-processing enzyme, FES upstream region, FUR, FURIN, Furin membrane associated receptor protein, FURIN_HUMAN, PACE, Paired basic amino acid residue cleaving enzyme, Paired basic amino acid residue-cleaving enzyme, PCSK3, Proprotein convertase subtilisin/kexin type 3, SPC1|FURIN
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Human
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: D108-E715
- Spezies:
- Human
- Uniprot:
- P09958
- Synonyme:
- dibasic processing enzyme;Dibasic-processing enzyme;FES upstream region;FUR;furin;furin, membrane associated receptor protein;PACE;paired basic amino acid residue-cleaving enzyme;PCSK3;proprotein convertase subtilisin/kexin 3;proprotein convertase subtilisin/kexin type 3;SPC1;subtilisin-like proprotein convertase 1
- Weitere Details:
- Furin (Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The FUR gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance.
- Versandbedingungen:
- Blue Ice