Human PEDF - SerpinF1 ELISA Kit

Eine Lieferung in diese Region ist nicht möglich.

SKU:: KOA0537
Zusätzliche Namen:: Alpha 2 antiplasmin, Cell proliferation-inducing gene 35 protein, EPC1, OI12, OI6, PEDF, PEDF_HUMAN, PIG35, Pigment epithelium derived factor, Pigment epithelium-derived factor, Proliferation inducing protein 35, serine (or cysteine) proteinase inhibitor clade F (alpha-2 antiplasmin, pigment epithelium derived factor) member 1, SERPIN F1, Serpin peptidase inhibitor clade F member , |serpin peptidase inhibitor clade F (alpha-2 antiplasmin pigment epithelium derived factor) member 1,
Anwendung:: ELISA
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Reaktivitäten:: Human
Immunogen:: Expression system for standard: NSO; Immunogen sequence: M1-P418
Spezies:: Human
Uniprot:: P36955
Synonyme:: alpha-2 antiplasmin;cell proliferation-inducing gene 35 protein;EPC-1;OI12;OI6;PEDF;PIG35;pigment epithelium-derived factor;serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1;Serpin F1;serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1;testis tissue sperm-binding protein Li 70n
Weitere Details:: Pigment epithelium-derived factor (PEDF) is also known as serpin F1 (SERPINF1). In humans, it is encoded by the SERPINF1 gene. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. It suppresses retinal neovascularization and endothelial cell proliferation. And Antiangiogenic function is also conferred by PEDF through inhibition of both VEGFR-1 and VEGFR-2. In addition, the antitumorigenic effects of PEDF are not only due to inhibition of supporting vasculature, but also due to effects on the cancer cells themselves. PEDF is shown to inhibit cancer cell proliferation and increase apoptosis via the FAS/FASL pathway. Expression of PEDF in the human retina is found at 7.4 weeks of gestation, suggesting it may play a role in retinal neuron differentiation.

Versandbedingungen:: Blue Ice