Rat KIM1 ELISA Kit

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SKU:: KOA0531
Zusätzliche Namen:: HAVCR, HAVcr-1, Havcr1, HAVR1_HUMAN, Hepatitis A virus cellular receptor 1, Kidney injury molecule 1, KIM-1, T cell immunoglobin domain and mucin domain protein 1, T-cell immunoglobulin and mucin domain-containing protein 1, T-cell membrane protein 1, TIM, TIM-1, TIM1, TIMD-1, TIMD1|HAVCR1
Anwendung:: ELISA
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Reaktivitäten:: Rat
Immunogen:: Expression system for standard: NSO; Immunogen sequence: S18-V238
Spezies:: Rat
Uniprot:: O54947
Synonyme:: HAVcr-1;hepatitis A virus cellular receptor 1 homolog;kidney injury molecule 1;KIM-1;Kim1;t cell immunoglobulin and mucin domain-containing protein 1;TIMD-1
Weitere Details:: KIM1(TIM-1), also known as Hepatitis A virus cellular receptor 1, is a protein that in Rat is encoded by the HAVCR1 gene. Infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV led to conclude that the protein is indeed a receptor for the virus. Immunofluorescence microscopy demonstrated internalization of HAV by dog cells expressing HAVCR1. Using a monoclonal antibody to rat Tim1, Tim1 was expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. By homology of synteny with the rat Tim1 gene and database analysis, was mapped the HAVCR1 gene to 5q33.2.