KOA0519
Mouse TNFSF4 - OX40L ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0519
- Zusätzliche Namen:
- CD 134L, CD 252, CD134, CD134 ligand, CD134L, CD252, CD252 antigen, glycoprotein 34 kd, Glycoprotein Gp34, GP34, OX-40L, OX40 antigen ligand, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, TNFL4_HUMAN, Tnfsf4, Tumor necrosis factor (ligand) superfamily member 4, Tumor necrosis factor ligand superfamily member 4, TXGP1|TNFSF4
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Mouse
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: S51-L198
- Spezies:
- Mouse
- Uniprot:
- P43488
- Synonyme:
- Ath;Ath-;Ath-1;Ath1;atherosclerosis 1;CD134;CD134L;gp3;gp34;OX-40L;OX4;OX40 ligand;Ox40l;tax-transcriptionally activated glycoprotein 1 ligand;Tnlg2b;tumor necrosis factor ligand 2b;tumor necrosis factor ligand superfamily member 4;Txgp;TXGP1;Txgp1l
- Weitere Details:
- OX40L is the ligand for CD134 and is expressed on such cells as DC2s enabling amplification of Th2 cell differentiation. OX40L has also been designated CD252. By analysis of an interspecific backcross, Baum et al.(1994) mapped the mouse Tnfsf4 gene to chromosome 1. Using fluorescence in situ hybridization, they localized the human TNFSF4 gene to 1q25, a region sharing homology of synteny with the portion of mouse chromosome 1 containing the Tnfsf4 gene.OX40L strongly inhibited the generation of IL-10-producing Tr1 cells induced by two physiologic stimuli, the inducible costimulatory ligand and immature dendritic cells. In addition, OX40L strongly inhibited IL-10 production and suppressive function of differentiated IL-10-producing Tr1 cells. Tnfsf4 underlies Ath1 in mice and that polymorphisms in its human homolog TNFSF4 increase the risk of myocardial infarction in humans.
- Versandbedingungen:
- Blue Ice