KOA0482
Mouse MER - MERTK ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0482
- Zusätzliche Namen:
- C mer, c mer proto oncogene tyrosine kinase, MER receptor tyrosine kinase, Mertk, MERTK_HUMAN, Proto-oncogene c-Mer, Receptor tyrosine kinase MerTK, RP38, STK kinase, Tyrosine-protein kinase Mer|MERTK
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Mouse
- Immunogen:
- Expression system for standard: sf21; Immunogen sequence: E23-F498
- Spezies:
- Mouse
- Uniprot:
- Q60805
- Synonyme:
- c-mer proto-oncogene tyrosine kinase;Eyk;Me;Mer;nmf1;nmf12;Ny;Nyk;proto-oncogene c-Mer;proto-oncogene tyrosine-protein kinase Mer;receptor tyrosine kinase MerTK;Tyro 12;tyrosine-protein kinase Mer
- Weitere Details:
- Proto-oncogene tyrosine-protein kinase MER, also called MERTK is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type(immunoglobulin-like) domains, and one tyrosine kinase domain. This gene is mapped to 2q13. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium(RPE) as a regulator of rod outer segments fragments phagocytosis. This gene also plays an important role in inhibition of Toll-like receptors(TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
- Versandbedingungen:
- Blue Ice