KOA0446
Human EPCAM ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0446
- Zusätzliche Namen:
- 17 1A, 323/A3, AUA1, CD326, CD326 antigen, CO 17A, CO17 1A, CO17A, DIAR5, EGP2, EGP, EGP2, EGP314, EGP40, Ep CAM, Ep-CAM, EPCAM, ESA, GA733 1, GA733 2, GA733-2, hEGP 2, hEGP314, HNPCC8, KS1/4, KSA, M1S 1, M1S2 ,M4S1, MIC18 MK 1 ,TACD1, TACSTD1, TROP1|EPCAM
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Human
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: Q24-K265
- Spezies:
- Human
- Uniprot:
- P16422
- Synonyme:
- adenocarcinoma-associated antigen;cell surface glycoprotein Trop-1;DIAR5;EGP-2;EGP314;EGP40;epithelial cell adhesion molecule;Epithelial cell surface antigen;Epithelial glycoprotein;epithelial glycoprotein 314;ESA;HNPCC8;human epithelial glycoprotein-2;KS 1/4 antigen;KS1/4;KSA;M4S1;major gastrointestinal tumor-associated protein GA733-2;membrane component, chromosome 4, surface marker (35kD glycoprotein);MIC18;MK-1;TACSTD1;TROP1;trophoblast cell surface antigen 1;tumor-associated calcium signal transducer 1
- Weitere Details:
- Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. Also it is involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since it is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.
- Versandbedingungen:
- Blue Ice