KOA0412
Rat CD80 - B7-1 ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0412
- Zusätzliche Namen:
- Activation B7-1 antigen, B7, BB1, CD80, CD80_HUMAN, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD82|CD80
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Rat
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: I39-Q248
- Spezies:
- Rat
- Uniprot:
- O35187
- Synonyme:
- B7-1;Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1);CD80 antigen;CD80-like;T-lymphocyte activation antigen CD80
- Weitere Details:
- The protein CD80(Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7-1. The cDNA for B7-1 predicts a type I membrane protein, i.e., one synthesized with a signal peptide that is cleaved upon translocation across the endoplasmic membrane. The protein is predicted to contain 2 extracellular domains structurally similar to those of Ig, a hydrophobic transmembrane region, and a short cytoplasmic domain. The CD80 and CD86 genes encode B7-1 and B7-2, respectively, which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4.
- Versandbedingungen:
- Blue Ice