Mouse CD40L ELISA Kit

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SKU:: KOA0350
Zusätzliche Namen:: CD154, CD40 antigen ligand, CD40 ligand, CD40-L, CD40L_HUMAN, CD40LG, gp39, HIGM1, IGM, IMD3, soluble form, T B cell activating molecule, T BAM, T cell antigen Gp39, T-cell antigen Gp39, TNF related activation protein, TNF-related activation protein, TNFSF5, TrAP, Tumor necrosis factor (ligand) superfamily member 5, Tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome), Tumor necrosis factor ligand superfamily member 5|CD40LG
Anwendung:: ELISA
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Reaktivitäten:: Mouse
Immunogen:: Expression system for standard: NSO; Immunogen sequence: E61-L260
Spezies:: Mouse
Uniprot:: P27548
Synonyme:: CD154;Cd40;CD40 ligand;CD40-L;Cd40l;gp3;gp39;HIGM;HIGM1;IGM;IMD;IMD3;Ly-6;Ly-62;Ly62;T-BA;T-BAM;T-cell antigen Gp39;TNF-related activation protein;Tnfs;Tnfsf5;Tnlg8b;TRAP;tumor necrosis factor ligand 8b;tumor necrosis factor ligand superfamily member 5
Weitere Details:: CD40 ligand(CD40L) is a type II membrane protein of 261 amino acids on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumour necrosis factor-alpha and -beta, and has important functions in B-cell activation and differentiation. Human CD40L with 5 exons, is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1, and can be detected on T cells but is absent from B cells and monocytes. Since CD40L is expressed on platelets and released from them on activation, its predictive value as a marker for clinical outcome and the therapeutic effect of inhibition of glycoprotein IIb/IIIa receptor in patients with acute coronary syndromes was investigated. The soluble CD40L may be involved in the process of restenosis and that it exerts its effect by triggering a complex group of inflammatory reactions on endothelial and mononuclear cells.CD40L plays a central role in the pathophysiology of acute coronary syndromes, and has a role in the pathogenesis o.

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