KOA0338
Mouse ACE ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0338
- Zusätzliche Namen:
- ACE|Angiotensin converting enzyme, CD143, DCP, Dcp1, Dipeptidyl carboxypeptidase I, Kininase II
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Mouse
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: L35-Q1264
- Spezies:
- Mouse
- Uniprot:
- P09470
- Synonyme:
- angiotensin-converting enzyme;AW208573;CD143;dipeptidyl carboxypeptidase I;dipeptidyl peptidase;kininase II
- Weitere Details:
- Angiotensin-converting enzyme(ACE), an exopeptidase, is a circulating enzyme that participates in the body's renin-angiotensin system(RAS), which mediates extracellular volume(i.e. that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. It is secreted by pulmonary and renal endothelial cells and catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II. Using a DNA marker at the growth hormone gene locus, which they characterized as 'extremely polymorphic' and which showed no recombination with ACE, ACE was mapped to 17q22-q24, consistent with the in situ hybridization mapping to 17q23. ACE, or kininase II, is a dipeptidyl carboxypeptidase that plays an important role in blood pressure regulation and electrolyte balance by hydrolyzing angiotensin I into angiotensin II, a potent vasopressor, and aldosterone-stimulating peptide. The enzyme is also able to inactivate bradykinin, a potent vasodilator.
- Versandbedingungen:
- Blue Ice