Human TGF beta 1 ELISA Kit

Eine Lieferung in diese Region ist nicht möglich.

SKU:: KOA0307
Zusätzliche Namen:: Camurati-Engelmann disease, CED, DPD1, LAP, Latency-associated peptide, TGF beta 1 protein, TGF-beta-1, TGFB, tgfb1, TGFB1_HUMAN, TGFbeta, Transforming growth factor beta 1|TGFB1
Anwendung:: ELISA
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Reaktivitäten:: Bovine, Canine, Human, Rabbit
Immunogen:: Expression system for standard: CHO; Immunogen sequence: A279-S390
Spezies:: Human
Uniprot:: P01137
Synonyme:: CED;DPD1;IBDIMDE;LAP;latency-associated peptide;prepro-transforming growth factor beta-1;TGF-beta-1;TGF-beta1;TGFB;TGFbeta;transforming growth factor beta-1 proprotein;transforming growth factor beta1
Weitere Details:: Transforming growth factor-beta1 (TGF-beta1) is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGF-beta and essentially all of them have specific receptors for this peptide. TGF-beta regulates the actions of many other peptide growth factors and determines a positive or negative direction of their effects. TGF-beta1 is known for its potent and diverse biological effects, including immune regulation, and cell growth and differentiation. TGF-beta1 is also an important mediator of bone remodeling. TGF-beta1, a potent keratinocyte growth inhibitor, has been shown to be overexpressed in keratinocytes in certain inflammatory skin diseases and has been thought to counteract the effects of other growth factors at the site of inflammation. TGF-beta1, a multifunctional cytokine with fibrogenic properties, has been implicated in the pathogenesis of the vascular and target organ complications of hypertension. TGF-beta1 may also regulate blood pressure via stimulation of endothelin-1 and/or renin secretion. TGF-beta1 is secreted as a latent form, which consists of its mature form and a latency-associated peptide (beta1-LAP) in either the presence or the absence of additional latent TGF-beta1-binding protein. The standard product used in this kit is recombinant TGF beta1 with the molecular mass of 25KDa.

Versandbedingungen:: Blue Ice