Human CCL22 - MDC ELISA Kit

Eine Lieferung in diese Region ist nicht möglich.

SKU:: KOA0255
Zusätzliche Namen:: A-152E5.1, ABCD 1, ABCD1, C-C motif chemokine 22, CC chemokine STCP-1, Ccl22, CCL22_HUMAN, Chemokine (C-C motif) ligand 22, DC/B-CK, Macrophage-derived chemokine, MDC(1-69), MDC(7-69), MGC34554, SCYA22, Small inducible cytokine A22, Small inducible cytokine subfamily A (Cys-Cys), member 22, Small-inducible cytokine A22, STCP 1, STCP1, Stimulated T cell chemotactic protein 1, Stimulated T-cell chemotactic protein 1|CCL22
Anwendung:: ELISA
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Reaktivitäten:: Human
Immunogen:: Expression system for standard: E.coli; Immunogen sequence: G25-Q93
Spezies:: Human
Uniprot:: O00626
Synonyme:: A-152E5.1;ABCD-1;C-C motif chemokine 22;CC chemokine STCP-1;chemokine (C-C motif) ligand 22;DC/B-CK;macrophage-derived chemokine;MDC;MDC(1-69);SCYA22;small inducible cytokine A22;small inducible cytokine subfamily A (Cys-Cys), member 22;Small-inducible cytokine A22;STCP-1;stimulated T cell chemotactic protein 1;Stimulated T-cell chemotactic protein 1
Weitere Details:: Macrophage-derived chemokine(MDC), also called Chemokine, cc motif, ligand 22(CCL22) or Small inducible cytokine subfamily A, member 22(SCY22). MDC is a recently identified member of the CC chemokine family. It is not closely related to other chemokines, sharing most similarity with thymus- and activation-regulated chemokine(TARC), which contains 37% identical amino acids. In addition, MDC gene is mapped to chromosome 16q13, the same position reported for the TARC gene. MDC has the four-cysteine motif and other highly conserved residues characteristic of CC chemokines, but it shares<35% identity with any of the known chemokines. Recombinant MDC was expressed in Chinese hamster ovary cells and purified by heparin-Sepharose chromatography. MDC is highly expressed in macrophages and in monocyte-derived dendritic cells, but not in monocytes, natural killer cells, or several cell lines of epithelial, endothelial, or fibroblast origin. High expression was also detected in normal thymus and less expression in lung and spleen. MDC is thus a unique member of the CC chemokine family that may play a fundamental role in the function of dendritic cells, natural killer cells, and monocytes.

Versandbedingungen:: Blue Ice