Mouse Leptin receptor ELISA Kit

Eine Lieferung in diese Region ist nicht möglich.

SKU:: KOA0249
Zusätzliche Namen:: CD295, HuB220, LEP-R, LEPR, LEPR_HUMAN, Leptin receptor, OB receptor, OB-R, OBR|LEPR
Anwendung:: ELISA
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Reaktivitäten:: Mouse
Immunogen:: Expression system for standard: NSO; Immunogen sequence: L22-G839
Spezies:: Mouse
Uniprot:: P48356
Synonyme:: B219;db;diabetes;LE;LEP-R;Leprb;LEPROT;leptin receptor;leptin receptor gene-related protein;Modb;Modb1;O;OB receptor;OB-;OB-RGRP;obese-;obese-like;obl;Obr
Weitere Details:: Leptin receptor(or Obese receptor, OBR) is a single membrane-spanning receptor most related to the gp130 signal-transducing component of the IL-6 receptor, the G-CSF receptor, and the LIF receptor. OB-R mRNA is expressed not only in choroid plexus, but also in several other tissues, including hypothalamus. Leptin acts through the leptin receptor, a single-transmembrane domain receptor of the cytokine-receptor family. Leptin controls energy balance and food intake through the leptin receptor in the hypothalamus of the brain, which suggests that some polymorphisms of the leptin receptor gene(LEPR) might contribute to obesity or obesity-related diseases. Leptin is also involved in the regulation of blood pressure through the leptin receptor.