KOA0246
Human Leptin ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0246
- Zusätzliche Namen:
- CD295, HuB219, LEP-R, LEPR, LEPR_HUMAN, Leptin receptor, OB receptor, OB-R, OBR|LEP
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Human
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: V22-C167
- Spezies:
- Human
- Uniprot:
- A4D0Y8
- Synonyme:
- LEPD;leptin;leptin (murine obesity homolog);leptin (obesity homolog, mouse);OB;obese protein;obese, mouse, homolog of;obesity factor;OBS
- Weitere Details:
- Leptin(or obese, OB) is a circulating hormone that is expressed abundantly and specifically in the adipose tissue. Human ob protein is a 166-amino acid polypeptide with a putative signal sequence and is 84 and 83% homologous to the mouse and rat ob proteins, respectively. Northern blot analysis reveals that OB RNA is present at a high level in adipose tissue but at much lower levels in placenta and heart. Indeed, Leptin is first described as an adipocyte-derived signalling factor, which, after interaction with its receptors, induces a complex response including control of bodyweight and energy expenditure. Leptin seems in addition to its role in metabolic control to have important roles in reproduction and neuroendocrine signalling. Leptin is a powerful inhibitor of bone formation in vivo. Comparative mapping of mouse and human DNA indicates that the ob gene is located within a region of mouse chromosome 6 that is homologous to a portion of human chromosome 7q. The standard product used in this kit is recombinant human Leptin.
- Versandbedingungen:
- Blue Ice