KOA0241
Human IL-17 ELISA Kit

Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0241
- Zusätzliche Namen:
- CTLA 8, CTLA-8, CTLA8, Cytotoxic T lymphocyte associated antigen 8, Cytotoxic T lymphocyte associated protein 8, Cytotoxic T lymphocyte associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL 17, IL 17A, IL-17, IL-17A, IL17_HUMAN, Il17a, Interleukin 17A, Interleukin-17A, Interleukin17, Interleukin17A|IL17A
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Human
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: I20-A155
- Spezies:
- Human
- Uniprot:
- Q16552
- Synonyme:
- CTLA-8;CTLA8;cytotoxic T-lymphocyte-associated antigen 8;cytotoxic T-lymphocyte-associated protein 8;IL-17;IL-17A;IL17;ILA17;interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8);interleukin-17;interleukin-17A
- Weitere Details:
- IL-17 is an inflammatory cytokine produced primarily by a unique lineage of CD4 T cells that plays critical roles in the pathogenesis of multiple autoimmune diseases. Interleukin-17 is expressed by activated T cells and is 57% identical to the 17- to 26-kD secretory glycoprotein encoded by gene 13 of the herpesvirus saimiri (HVS-13). IL17 induces nuclear factor kappa-B and the expression of IL6, intercellular adhesion molecule-1, granulocyte macrophage colony-stimulating factor, and prostaglandin E2, as well as the maturation of CD34 positive hematopoietic precursors into neutrophils. Anti-IL17 antibodies significantly inhibited osteoclast formation induced by culture media of RA synovial tissues. The standard product used in this kit is recombinant human IL-17, consisting of 136 amino acids with the molecular mass of 16KDa.
- Versandbedingungen:
- Blue Ice
