Human IGFBP2 ELISA Kit

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SKU:: KOA0201
Zusätzliche Namen:: BP 2, BP2, IBP 2, IBP-2, IBP2, IBP2_HUMAN, IGF binding protein 2, IGF BP53, IGF-binding protein 2, IGF-BP53, IGFBP-2, IGFBP2, IGFBP53, Insulin Like Growth Factor Binding Protein 2, Insulin like growth factor binding protein 2 36kDa, Insulin like growth factor-binding protein 2 precursor, Insulin-like growth factor-binding protein 2|IGFBP2
Anwendung:: ELISA
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Reaktivitäten:: Human
Immunogen:: Expression system for standard: NSO; Immunogen sequence: E40-Q328
Spezies:: Human
Uniprot:: P18065
Synonyme:: IBP2;IGF-binding protein 2;IGF-BP53;insulin-like growth factor binding protein 2, 36kDa;insulin-like growth factor-binding protein 2
Weitere Details:: Insulin-like growth factor-binding protein 2(IGFBP2), also called IBP2, is a protein that in humans is encoded by the IGFBP2 gene. It is mapped to 2q35. By structural analysis, it showed that the IGFBP2 gene consists of 4 exons with 3 introns of lengths 27.0, 1.0, and 1.9 kb. IGFBP2 secreted by metastatic cells recruits endothelia by modulating IGF1 mediated activation of the IGF type-I receptor on endothelial cells. The IGFBP2/IGF1/IGF1R and GAS6/MERTK signaling pathways are regulators of cancer-mediated endothelial recruitment.