KOA0179
Mouse G-CSF ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0179
- Zusätzliche Namen:
- C17orf33, Colony stimulating factor 3 (granulocyte), CSF 3, CSF beta, CSF3, CSF3OS, Csfg, Filgrastim, GCSA, GCSF, Granulocyte colony stimulating fact, Lenograstim, Macrophage granulocyte inducer 2,MGC45931, MGI 2, MGI IG, OTTMUSP00000006785, Pluripoietin, RP23-395E10.4|CSF3
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Mouse
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: V31-A208
- Spezies:
- Mouse
- Uniprot:
- P09920
- Synonyme:
- Csf;Csfg;G-CS;G-CSF;granulocyte colony-stimulating factor;MGI-;MGI-IG
- Weitere Details:
- Granulocyte colony-stimulating factor(G-CSF) is a member of the CSF family of hormone-like glycoprotein that regulates hematopoietic cell proliferation and differentiation, and it almost exclusively stimulates the colony formation of granulocytes from committed precursor cells in semi-solid agar culture. G-CSF is also termed colony stimulating factor-3, and a single gene of which codes for a 177 or 180 amino acid mature protein of molecular weight 19,600. Functionally, it specifically stimulates the proliferation and differentiation of the progenitor cells for granulocytes. The effect of G-CSF on myeloid leukemias is unique among colony stimulating factors in driving the leukemic cells from a self-renewing malignant state to a mature differentiated phenotype with the concomitant loss of tumorigenicity. Besides, it also prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes. The recombinant form of hG-CSF is capable of supporting neutrophil proliferation in a CFU-GM assay as well as early erythroid colonies and mixed colony formation. Human gene coding for G-CSF is assigned to the q21-q22 region of chromosome 17.3 The standard product used in this kit is recombinant Mouse G-csf, consisting of 179 amino acids with the molecular mass of 19KDa.
- Versandbedingungen:
- Blue Ice