KOA0166
Mouse FASL ELISA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- KOA0166
- Zusätzliche Namen:
- Apoptosis (APO 1) antigen ligand 1, Apoptosis antigen ligand, APT1LG1, APTL, CD178, CD95 L, CD95 ligand, CD95L, CD95L protein, Fas antigen ligand, FASL, FASLG, TNF superfamily member 6, TNFSF6, Tumor necrosis factor (ligand) superfamily member 6, Tumor necrosis factor ligand superfamily member 6|FASLG
- Anwendung:
- ELISA
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Reaktivitäten:
- Mouse
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: P132-L279
- Spezies:
- Mouse
- Uniprot:
- P25446
- Synonyme:
- AI196731;AP;apo-1 antigen;APO1;apoptosis-mediating surface antigen FAS;APT1;CD95;Fas (TNF receptor superfamily member);Fas antigen;FASLG receptor;lpr;lymphoproliferation;TNF;Tnfr;TNFR6;Tnfrsf6;tumor necrosis factor receptor superfamily member 6
- Weitere Details:
- FAS Ligand (FASL) is a 40 kDa type II membrane protein belonging to the tumor necrosis factor family, which induces apoptosis by binding to its receptor, Fas. The human FasL gene consists of approximately 8.0 kb and is split into four exons. This gene consists of 281 amino acids with a calculated M(r) of 31,759 and was mapped on chromosome 1q23. It has an identity of 76.9% at the amino acid sequence level with mouse FasL. The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis. FAS and FASL triggered apoptosis pathway plays an important role in human carcinogenesis. This system may also play a role in modulating the genetic susceptibility of mouse strains to develop T-cell lymphoblastic lymphomas.
- Versandbedingungen:
- Blue Ice