K-I51
AKT1 Antibody Combo Pack
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- K-I51
- Zusätzliche Namen:
- AKT 1 antibody pair, AKT-1, PKB antibody, PKB gamma antibody, PKBGAMMA antibody, PRKBG antibody, Protein kinase Akt 1 antibody, Protein kinase B gamma antibody, RAC-gamma serine/threonine-protein kinase, RAC-PK-gamma, primary and secondary antibody pair, Primary+Secondary pair, matched antibody pair|AKT1
- Anwendung:
- ELISA, Flow Cytometry, IHC, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid and Lyophilized
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-AKT1 Antibody was produced by repeated immunizations in mice with a synthetic peptide corresponding to internal residues of human AKT1 protein. Anti-Mouse IgG HRP secondary antibody was produced by repeated immunizations in rabbit with Mouse IgG whole molecule.
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Klon:
- 14E5.A2.B2.H9
- Uniprot:
- P31749
- Synonyme:
- AKT;AKT1m;PKB;PKB alpha;PKB-ALPHA;PRKBA;Protein kinase B;protein kinase B alpha;proto-oncogene c-Akt;RAC;rac protein kinase alpha;RAC-ALPHA;RAC-alpha serine/threonine-protein kinase;RAC-PK-alpha;serine-threonine protein kinase;v-akt murine thymoma viral oncogene homolog 1;v-akt murine thymoma viral oncogene-like protein 1
- Weitere Details:
- This AKT1 Antibody Combo Pack contains: Mouse Anti-AKT1 and Rabbit Anti-Mouse IgG 1, 2a, 2b, 3 HRP Antibody. AKT1 Antibody detects AKT1 which is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis; (ii) promotion of proliferation. Anti-AKT1 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience and Signal Transduction research.
- Versandbedingungen:
- Dry Ice