K-BR8
AKT2 Antibody Combo Pack
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- K-BR8
- Zusätzliche Namen:
- AKT 2 antibody pair, AKT-2, PKB antibody, PKB gamma antibody, PKBGAMMA antibody, PRKBG antibody, Protein kinase Akt 2 antibody, Protein kinase B gamma antibody, RAC-gamma serine/threonine-protein kinase, RAC-PK-gamma, primary and secondary antibody pair, Primary+Secondary pair, matched antibody pair|AKT2
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid and Lyophilized
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-AKT2 Antibody was produced in mice by repeated immunizations with a synthetic peptide corresponding to internal residues of human AKT2 protein. Anti-Mouse IgG HRP secondary antibody was produced by repeated immunizations in rabbits with Mouse IgG whole molecule.
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Klon:
- 16C8.E4.G7.E9
- Uniprot:
- P31751, Q9Y243
- Synonyme:
- HIHGHH;MPPH;MPPH2;murine thymoma viral (v-akt) homolog-2;PKB beta;PKB gamma;PKB-GAMMA;PKBB;PKBBETA;PKBG;PRKBB;PRKBG;protein kinase Akt-2;Protein kinase Akt-3;protein kinase B beta;Protein kinase B gamma;putative v-akt murine thymoma viral oncoprotein 2;rac protein kinase beta;RAC-BETA;RAC-beta serine/threonine-protein kinase;RAC-gamma;RAC-gamma serine/threonine protein kinase;RAC-gamma serine/threonine-protein kinase;RAC-PK-beta;RAC-PK-gamma;STK-2;v-akt murine thymoma viral oncogene homolog 2;v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
- Weitere Details:
- This primary and secondary antibody pair comes with matched antibody pairs to detect and quantify endogenous protein levels of human AKT2. AKT2 Antibody detects AKT2 which is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis; (ii) promotion of proliferation. Anti-AKT2 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience and Signal Transduction research.
- Versandbedingungen:
- Dry Ice