c-erbB2 Antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: 900-C01-B37
Zusätzliche Namen:: ERBB2|rabbit anti-c-erbB2 Antibody, Receptor tyrosine-protein kinase erbB-2, p185erbB2, C-erbB-2, NEU proto-oncogene, tyrosine kinase-type cell surface receptor HER2, MLN 19, CD340
Anwendung:: ELISA, IHC, WB
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: erbB2 monoclonal antibody was produced by repeated immunizations with a recombinant protein corresponding to amino acid residues encoding the extracellular domain of human c-erbB2 protein. The hybridoma was produced by fusing New Zealand White rabbit splenocytes and myeloma cells using conventional technology.
Klon:: SP3
Uniprot:: P04626
Synonyme:: c-erb B2/neu protein;CD340;HER-2;HER-2/neu;HER2;herstatin;human epidermal growth factor receptor 2;metastatic lymph node gene 19 protein;MLN 19;NEU;neuro/glioblastoma derived oncogene homolog;neuroblastoma/glioblastoma derived oncogene homolog;NGL;p185erbB2;proto-oncogene c-ErbB-2;proto-oncogene Neu;receptor tyrosine-protein kinase erbB-2;TKR1;tyrosine kinase-type cell surface receptor HER2;v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2;v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2;v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog;VSCN2
Weitere Details:: The ERBB2 gene encodes a member of the tyrosine protein kinase superfamily that is an essential component of a neuregulin-receptor complex called c-erbB2 (also known as Receptor tyrosine-protein kinase erbB-2, p185erbB2, C-erbB-2, NEU proto-oncogene, tyrosine kinase-type cell surface receptor HER2, MLN 19 and CD340), although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. C-erbB2 is not activated by EGF, TGF-alpha and amphiregulin. Defects in ERBB2 are associated with gastric cancer, familial glioma of brain (glioblastoma multiforme), ovarian cancer and lung cancer (adenocarcinoma of lung). c-erbB2 antibody is ideal for Cancer and Signal Transduction research.

Versandbedingungen:: Blue Ice