900-301-C85
NMDA NR1 Subunit Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 900-301-C85
- Zusätzliche Namen:
- Grin1|mouse anti-NMDA NR1 Antibody, Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1, NMD-R1, Grin1
- Anwendung:
- IHC, WB, IP
- Physischer Zustand:
- Lyophilized
- Spezies-Reaktivität:
- Rat
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Host:
- Mouse
- Reaktivitäten:
- Mouse, Rat
- Immunogen:
- Anti-NMDA NR1 Subunit Antibody was produced by repeated immunizations with a fusion proteins containing amino acids 1-564 of the rat NR1 subunit of the NMDA receptor.
- Klon:
- R1JHL
- Uniprot:
- P35439
- Synonyme:
- GluN1;glutamate [NMDA] receptor subunit zeta-1;glutamate receptor ionotropic, NMDA 1;glutamate receptor, ionotropic, N-methyl D-aspartate 1;N-methyl-D-aspartate glutamate receptor;N-methyl-D-aspartate receptor subunit NR1;neurotransmitter receptor;NMD-R1;NMDA R1 receptor C1 cassette;NMDAR1;NR1
- Weitere Details:
- NMDA NR1 Subunit antibody detects NMDA NR1 receptor protein. The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and A Alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1-subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. NMDA NR1 Subunit antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research.
- Versandbedingungen:
- Ambient