612-401-E39
Synaptotagmin phospho S309 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 612-401-E39
- Zusätzliche Namen:
- Synaptotagmin-1, Synaptotagmin I, SytI, p65, Syt1|Syt1
- Anwendung:
- IHC, WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Rat
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Rat
- Buffer:
- 0.01 M HEPES, 0.15 M Sodium Chloride
- Immunogen:
- Anti-Synaptotagmin pS309 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser309 of Synaptotagmin.
- Formulierung:
- 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
- Uniprot:
- P21707
- Synonyme:
- P65;synaptotagmin I;synaptotagmin-1;sytI
- Weitere Details:
- Synaptotagmin 1 pS309 Antibody detects Synaptotagmin 1, which is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS. It is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release. Recent studies indicate that synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion. It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size. Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin's ability to influence both the exocytotic and endocytotic components of synaptic transmission. Anti-Synaptotagmin 1 pS309 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
- Versandbedingungen:
- Dry Ice