PAK 1/2/3 phospho T402 Antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: 612-401-E05
Zusätzliche Namen:: Pak1/2/3|Serine/threonine-protein kinase PAK 1, Alpha-PAK, Protein kinase MUK2, p21-activated kinase 1, p68-PAK
Anwendung:: WB
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Rat
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Host:: Rabbit
Reaktivitäten:: Rat
Buffer:: 0.01 M HEPES, 0.15 M Sodium Chloride
Immunogen:: Anti-PAK 1/2/3 pT402 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Thr402.
Formulierung:: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Uniprot:: P35465
Synonyme:: alpha-PAK;p21 (CDKN1A)-activated kinase 1;p21 protein (Cdc42/Rac)-activated kinase 1;p21-activated kinase 1;p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related);p68-PAK;PAK-1;protein kinase MUK2;serine/threonine-protein kinase PAK 1
Weitere Details:: PAK 1/2/3 pT402 Antibody detects PAK 1/2/3 pT402 proteins. In mammals, there are several identified isoforms of p21-activated protein kinases or PAKs: A Alpha-PAK (also known as PAK-1) and B Beta-PAK (also known as PAK-3) are mostly brain-specific, while -PAK (also known as PAK-2) is expressed ubiquitously. Mutations of the gene coding for PAK-3 are associated with X-linked mental retardation and recent work indicates that PAK-3 is a key regulator of synapse formation and plasticity in the hippocampus. PAK-3 is thought to play a key role in regulation of cell shape and motility as well as cell death. Autophosphorylation of Thr402 in the protein has been found to be essential for activation of PAK. Anti-PAK 1/2/3 pT402 Antibody is ideal for investigators involved in Neuroscience and Apoptosis research.

Versandbedingungen:: Dry Ice