612-401-C88
NMDA NR2B Subunit phospho Y1336 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 612-401-C88
- Zusätzliche Namen:
- Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, NR2B, Grin2b|Grin2b
- Anwendung:
- IHC, WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Rat
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- 0.01 M HEPES, 0.15 M Sodium Chloride
- Immunogen:
- Anti-NMDA NR2B Subunit pY1336 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1336.
- Formulierung:
- 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
- Uniprot:
- Q00960
- Synonyme:
- GluN2B;glutamate [NMDA] receptor subunit epsilon-2;glutamate receptor ionotropic, NMDA 2B;glutamate receptor, ionotropic, N-methyl D-aspartate 2B;glutamate receptor, ionotropic, NMDA2B;N-methyl D-aspartate receptor subtype 2B;NMDAR2B;NR2B
- Weitere Details:
- NMDA 2B pY1336 antibody detects NMDA 2B receptor protein. The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Phosphorylation of Tyr1336 is thought to potentiate NMDA receptor-dependent influx of calcium and ischemia may also increase the phosphorylation of this site. NMDA NR2B Subunit pY1336 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research.
- Versandbedingungen:
- Dry Ice