600-401-P67
AGER/RAGE Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-P67
- Zusätzliche Namen:
- AGER|Receptor for advanced glycosylation end products
- Anwendung:
- IHC, WB, IF
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Lyophilized
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3
- Immunogen:
- AGER/RAGE affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human RAGE.
- Formulierung:
- 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3
- Uniprot:
- Q15109
- Synonyme:
- advanced glycosylation end product-specific receptor;RAGE;receptor for advanced glycation end-products variant 20;Receptor for advanced glycosylation end products;SCARJ1;sRAGE
- Weitere Details:
- The receptor for advanced glycation end products (RAGE) is a multi-ligand member of the immunoglobulin superfamily of cell surface molecules. It interacts with distinct molecules implicated in homeostasis, development and inflammation, and certain diseases such as diabetes and Alzheimer's disease. RAGE is also a central cell surface receptor for amphoterin and EN-RAGE. RAGE is associated with sustained NF-kappaB activation in the diabetic microenvironment and has a central role in sensory neuronal dysfunction. Moreover, RAGE propagates cellular dysfunction in several inflammatory disorders and diabetes, and it also functions as an endothelial adhesion receptor promoting leukocyte recruitment. This antibody is suitable for researchers interested in neuroscience research.
- Versandbedingungen:
- Ambient