600-401-H20
ST2 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-H20
- Zusätzliche Namen:
- Il1rl1|Ly84, St2, Ste2, Interleukin-1 receptor-like 1, Interleukin-33 receptor alpha chain1, Lymphocyte antigen 84, Protein ST2, Protein T1
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- ST2 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to amino acids at the n-terminus of mouse ST2. This peptide is common to all three known ST2 isoforms.
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- P14719
- Synonyme:
- DER;DER4;Fit-;Fit-1;interleukin-1 receptor-like 1;interleukin-33 receptor alpha chain;Ly8;Ly84;lymphocyte antigen 84;Protein ST2;Protein T1;ST;St2;St2-;St2-rs1;ST2L;T1;T1/ST;T1/ST2
- Weitere Details:
- ST2 antibody detects mouse ST2 and is common to all three isoforms. ST2 is a member of a superfamily containing the interleukin-1 receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF. More recently, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor (TLR) 4 signaling and to maintain endotoxin tolerance. It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP. Anti-ST2 antibodies are ideal for investigators involved in cytokine and growth factors research.
- Versandbedingungen:
- Dry Ice