600-401-H00
IRF7 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-H00
- Zusätzliche Namen:
- Interferon regulatory factor 7|IRF7
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- IRF7 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to the c-terminus of human IRF7.
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- Q92985
- Synonyme:
- IMD39;interferon regulatory factor 7;interferon regulatory factor-7H;IRF-7;IRF-7H;IRF7A;IRF7B;IRF7C;IRF7H
- Weitere Details:
- IRF7 antibody detects the human IRF7. Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established. Anti-IRF7 antibodies are ideal for investigators involved in transcription factors, infectious disease and cytokines and growth factors research.
- Versandbedingungen:
- Dry Ice