600-401-G72
Adiponectin Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-G72
- Zusätzliche Namen:
- ACDC, ACRP30, APM1, GBP28|ADIPOQ
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Adiponectin Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide from near the c-terminus of human adiponectin.
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- Q15848
- Synonyme:
- 30 kDa adipocyte complement-related protein;ACDC;ACRP30;adipocyte complement-related 30 kDa protein;Adipocyte, C1q and collagen domain-containing protein;adiponectin;adipose most abundant gene transcript 1 protein;adipose specific collagen-like factor;ADIPQTL1;ADPN;APM-1;APM1;GBP28;Gelatin-binding protein;gelatin-binding protein 28
- Weitere Details:
- Adiponectin antibody detects human adiponectin. Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike the CTRPs, which are expressed in a wide variety of tissues, adiponectin is reported to be expressed exclusively by differentiated adipocytes. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. It is present in high levels in normal human plasma, but is reduced in obese subjects and often in those with increased insulin resistance and type 2 diabetes, suggesting that adiponectin may be a useful pharmacological target in various metabolic diseases. Anti-Adiponectin antibodies are ideal for investigators involved in glucose energy metabolism and apolipoprotein research.
- Versandbedingungen:
- Dry Ice