600-401-FU5
ULK2 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-FU5
- Zusätzliche Namen:
- ULK2|ULK2 Antibody, ATG1B, Unc51.2, KIAA0623, Unc-51-like kinase 2
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-ULK2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the internal region of human ULK2.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q8IYT8
- Synonyme:
- ATG1B;serine/threonine-protein kinase ULK2;Unc-51-like kinase 2;Unc51.2
- Weitere Details:
- ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.
- Versandbedingungen:
- Dry Ice