600-401-FS2
TSPY1S Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-FS2
- Zusätzliche Namen:
- TSPY1|TSPY1S Antibody, CT78, TSPY, DYS14, pJA923, Testis-specific Y-encoded protein 1, CT78
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti- TSPY1S antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid peptide near the C-terminus of human TSPY1S.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q01534
- Synonyme:
- cancer/testis antigen 78;CT78;DYS14;pJA923;testis specific protein, Y-linked;testis-specific Y-encoded protein 1;Testis-specific Y-encoded protein 10;testis-specific Y-encoded protein 3;TSPY;TSPY1;TSPY10;TSPY3
- Weitere Details:
- Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
- Versandbedingungen:
- Dry Ice