600-401-FR2
TSC22D3 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-FR2
- Zusätzliche Namen:
- TSC22D3|TSC22D3 Antibody, DIP, GILZ, hDIP, DSIPI, TSC-22R, TSC22 domain family protein 3, DSIP-immunoreactive peptide, Protein DIP
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti- TSC22D3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the N-terminus of human TSC22D3.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q99576
- Synonyme:
- delta sleep-inducing peptide immunoreactor;DIP;DSIP-immunoreactive leucine zipper protein;DSIP-immunoreactive peptide;DSIPI;GILZ;glucocorticoid-induced leucine zipper protein;TSC-22 related protein;TSC-22-like protein;TSC-22-related protein;TSC-22R;TSC22 domain family protein 3
- Weitere Details:
- The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-kB and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-kB. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.
- Versandbedingungen:
- Blue Ice