600-401-EV8
STEAP3 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-EV8
- Zusätzliche Namen:
- STEAP3|STEAP3 Antibody, STMP3, TSAP6, AHMIO2, dudlin-2, Metalloreductase STEAP3, Dudulin-2, hTSAP6
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-STEAP3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the N-terminus of human STEAP3.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q658P3
- Synonyme:
- AHMIO2;dudlin-2;dudulin-2;metalloreductase STEAP3;pHyde;six-transmembrane epithelial antigen of prostate 3;STEAP family member 3, metalloreductase;STMP3;TSAP6;tumor suppressor pHyde;tumor suppressor-activated pathway protein 6
- Weitere Details:
- The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
- Versandbedingungen:
- Dry Ice