600-401-EV1
SRPX2 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-EV1
- Zusätzliche Namen:
- SRPX2|SRPX2 Antibody, BPP, CBPS, PMGX, RESDX, SRPUL, Sushi repeat-containing protein SRPX2, Sushi-repeat protein upregulated in leukemia
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-SRPX2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide from near the N-terminus of human SRPX2.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- O60687
- Synonyme:
- BPP;CBPS;PMGX;RESDX;SRPUL;sushi repeat-containing protein SRPX2;sushi-repeat protein up-regulated in leukemia;sushi-repeat protein upregulated in leukemia
- Weitere Details:
- Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.
- Versandbedingungen:
- Blue Ice