600-401-EP4
SLC35D2 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-EP4
- Zusätzliche Namen:
- SLC35D2|SLC35D2 Antibody, hfrc, HFRC1, SQV7L, UGTrel8, HFRC, UGTREL8, Homolog of Fringe connection protein 1
- Anwendung:
- ELISA, IHC, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-SLC35D2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the C-terminus of human SLC35D2.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q76EJ3
- Synonyme:
- fringe connection;hfrc;HFRC1;homolog of Fringe connection protein 1;solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2;Solute carrier family 35 member D2;SQV7-like protein;SQV7L;UDP-galactose transporter-related protein 8;UDP-N-acetylglucosamine transporter;UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter;UGTrel8
- Weitere Details:
- The solute carrier family SLC35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident SLC family member SLC35D2 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. Its overexpression in transfected cells modulated cell surface heparin sulfate expression, suggesting that SLC35D2 is involved in heparin sulfate synthesis. SLC35D2-overexpressing cells also showed increased constitutive and hypotonic stress-stimulated release of UDP-GlcNAc, suggesting that SLC35D2 may be involved in UDP-sugar release and cell signaling.
- Versandbedingungen:
- Dry Ice